Review of "The Ten Most Wanted Solutions in Protein Bioinformatics", by Anna Tramontano

Bioinformatics can be defined as the application of computational tools to manage and analyze biological data, typically at the molecular level. The field of Computational Biology aims at the mathematical or computational modeling of biological processes, such as protein folding or protein-protein interaction. Many books that include the title bioinformatics or computational biology (BCB) actually present a mixture of the two fields. It is sometimes not possible to separate the two as for a single problem such as protein folding both bioinformatics techniques such as similarity search of existing protein databases as well as computational biology is used in the form of mathematically modeling the protein structure via thermodynamic models that are optimized via a computational technique.